SIRT1 Protects Against Apoptosis by Promoting Autophagy in the Oxygen Glucose Deprivation/Reperfusion-Induced Injury
Silent information regulator 1 (SIRT1) contributes to cellular regulation.Previous studies have reported SIRT1 to be abnormally expressed in the ischemic penumbra of cerebral ischemia/reperfusion (I/R) injury rat model.We investigated the effect of SIRT1 on oxygen and glucose deprivation/reperfusion (OGD/R) cell injury.Over-expressed or silenced SI